当前位置:
X-MOL 学术
›
npj Prim. Care Respir. Med.
›
论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
A multinational observational study identifying primary care patients at risk of overestimation of asthma control.
npj Primary Care Respiratory Medicine ( IF 3.1 ) Pub Date : 2019-12-05 , DOI: 10.1038/s41533-019-0156-4 Vicky Kritikos 1, 2 , David Price 3, 4, 5 , Alberto Papi 6 , Antonio Infantino 7 , Bjorn Ställberg 8 , Dermot Ryan 3, 9 , Federico Lavorini 10 , Henry Chrystyn 11 , John Haughney 12 , Karin Lisspers 8 , Kevin Gruffydd-Jones 13 , Miguel Román Rodríguez 14 , Svein Høegh Henrichsen 15 , Thys van der Molen 16 , Victoria Carter 3, 4 , Sinthia Bosnic-Anticevich 1, 17, 18
npj Primary Care Respiratory Medicine ( IF 3.1 ) Pub Date : 2019-12-05 , DOI: 10.1038/s41533-019-0156-4 Vicky Kritikos 1, 2 , David Price 3, 4, 5 , Alberto Papi 6 , Antonio Infantino 7 , Bjorn Ställberg 8 , Dermot Ryan 3, 9 , Federico Lavorini 10 , Henry Chrystyn 11 , John Haughney 12 , Karin Lisspers 8 , Kevin Gruffydd-Jones 13 , Miguel Román Rodríguez 14 , Svein Høegh Henrichsen 15 , Thys van der Molen 16 , Victoria Carter 3, 4 , Sinthia Bosnic-Anticevich 1, 17, 18
Affiliation
Factors related to the discrepancy between patient-perceived and actual disease control remain unclear. Identifying patients at risk of overestimation of asthma control remains elusive. This study aimed to (i) investigate the relationship between patient-reported and actual level of asthma control (ii), compare the characteristics between patients who believe their asthma is well controlled that accurately report 'well-controlled' asthma with those that do not, and (iii) identify factors associated with inaccurately reported 'well-controlled' asthma. A historical, multinational, cross-sectional study using data from the iHARP (initiative Helping Asthma in Real-life Patients) review service for adults with asthma prescribed fixed-dose combination therapy. Data from 4274 patients were analysed. A major discrepancy between patient-reported and Global Initiative for Asthma defined asthma control was detected; 71.1% of patients who reported 'well-controlled' asthma were inaccurate in their perception despite receiving regular maintenance therapy. Significant differences were noted in age, gender, body mass index, education level, medication use, side effects, attitudes to preventer inhaler use, inhaler technique review and respiratory specialist review between patients who accurately reported 'well-controlled' asthma and those who did not. Independent risk factors associated with inaccurately reported 'well-controlled' asthma were: having taken a maximum of 5-12 puffs or more of reliever inhaler on at least one day within the previous 4 weeks; being female; having seen a respiratory specialist more than a year ago (rather than in the previous year); and having required oral corticosteroids for worsening asthma in the previous year. The study highlighted the significant hidden burden associated with under-recognition of poor asthma control, on the part of the patient and the need for targeted interventions designed to address the continuing discrepancy between perceived and actual disease control.
中文翻译:
一项多国观察性研究确定了可能高估哮喘控制风险的初级保健患者。
与患者感知的疾病控制和实际疾病控制之间的差异有关的因素仍然不清楚。仍无法确定高估哮喘控制风险的患者。这项研究旨在(i)研究患者报告的哮喘水平与实际哮喘控制水平之间的关系(ii)比较那些认为其哮喘得到了良好控制,能够准确报告“良好控制的”哮喘的患者与没有哮喘的患者之间的特征,以及(iii)确定与错误报告的“控制良好”的哮喘有关的因素。一项历史性,跨国性,横断面研究,使用来自iHARP(现实生活中患者的初始帮助性哮喘)回顾服务的成人哮喘开处方固定剂量联合治疗服务。分析了来自4274名患者的数据。发现了患者报告的哮喘病与全球哮喘定义的哮喘控制方案之间的主要差异;尽管接受定期维持治疗,但仍有71.1%的报告称“控制良好”的哮喘患者的感知不准确。在年龄,性别,体重指数,教育水平,药物使用,副作用,对预防剂吸入剂的使用态度,吸入剂技术审查和呼吸专科医生审查之间,在准确报告“良好控制的”哮喘的患者与那些确实报告了哮喘的患者之间,存在显着差异。不是。与错误报告的“控制良好”的哮喘有关的独立危险因素是:在过去4周内至少一天最多服用5-12口喘气或更多的缓解剂吸入剂;是女性 一年多前(而不是前一年)见过呼吸专科医生;并在过去一年中需要口服皮质类固醇激素来加剧哮喘。该研究强调,患者对哮喘控制不佳的认识不足,隐藏着沉重的负担,需要有针对性的干预措施,以解决感知到的疾病控制与实际疾病控制之间的持续差异。
更新日期:2019-12-05
中文翻译:
一项多国观察性研究确定了可能高估哮喘控制风险的初级保健患者。
与患者感知的疾病控制和实际疾病控制之间的差异有关的因素仍然不清楚。仍无法确定高估哮喘控制风险的患者。这项研究旨在(i)研究患者报告的哮喘水平与实际哮喘控制水平之间的关系(ii)比较那些认为其哮喘得到了良好控制,能够准确报告“良好控制的”哮喘的患者与没有哮喘的患者之间的特征,以及(iii)确定与错误报告的“控制良好”的哮喘有关的因素。一项历史性,跨国性,横断面研究,使用来自iHARP(现实生活中患者的初始帮助性哮喘)回顾服务的成人哮喘开处方固定剂量联合治疗服务。分析了来自4274名患者的数据。发现了患者报告的哮喘病与全球哮喘定义的哮喘控制方案之间的主要差异;尽管接受定期维持治疗,但仍有71.1%的报告称“控制良好”的哮喘患者的感知不准确。在年龄,性别,体重指数,教育水平,药物使用,副作用,对预防剂吸入剂的使用态度,吸入剂技术审查和呼吸专科医生审查之间,在准确报告“良好控制的”哮喘的患者与那些确实报告了哮喘的患者之间,存在显着差异。不是。与错误报告的“控制良好”的哮喘有关的独立危险因素是:在过去4周内至少一天最多服用5-12口喘气或更多的缓解剂吸入剂;是女性 一年多前(而不是前一年)见过呼吸专科医生;并在过去一年中需要口服皮质类固醇激素来加剧哮喘。该研究强调,患者对哮喘控制不佳的认识不足,隐藏着沉重的负担,需要有针对性的干预措施,以解决感知到的疾病控制与实际疾病控制之间的持续差异。