The Drosophila melanogaster foraging (for) gene is a well-established example of a gene with major effects on behavior and natural variation. This gene is best known for underlying the behavioral strategies of rover and sitter foraging larvae, having been mapped and named for this phenotype. Nevertheless, in the last three decades an extensive array of studies describing for's role as a modifier of behavior in a wide range of phenotypes, in both Drosophila and other organisms, has emerged. Furthermore, recent work reveals new insights into the genetic and molecular underpinnings of how for affects these phenotypes. In this article, we discuss the history of the for gene and its role in natural variation in behavior, plasticity, and behavioral pleiotropy, with special attention to recent findings on the molecular structure and transcriptional regulation of this gene.

中文翻译：

---

觅食基因及其行为效应：多效性和可塑性。

果蝇（Drosophila melanogaster）觅食（for）基因是对行为和自然变异有重大影响的基因的公认例子。该基因最著名的原因是它具有潜在的漫游者和保姆觅食幼虫的行为策略，并已对该表型进行了定位和命名。然而，在过去的三十年中，已经出现了广泛的研究，这些研究描述了果蝇在果蝇和其他生物中在多种表型中作为行为调节剂的作用。此外，最近的工作揭示了如何影响这些表型的遗传和分子基础的新见解。在本文中，我们讨论了for基因的历史及其在行为，可塑性和行为多效性的自然变异中的作用，