The chemical-pharmaceutical sector is facing an unprecedented fast-changing environment, with new market and technological trends impacting the companies’ operational strategies. Managing the pharmaceutical supply chain (PSC) operations is, therefore, ever more complex and challenging. The goal of this work is to present a comprehensive overview of the current state of the industry and research developments; and then, to develop a new decision-making reference framework to assist in the creation of optimization-based decision support models. This will be achieved through a multi-perspective analysis that encompasses strategic and tactical planning decision-making, in the current and future business context of the chemical-pharmaceutical industry. The findings reveal a lack of research addressing the most prominent trends currently driving this sector, such as patient centricity or new technological developments, thus highlighting the disruptive nature of the expected changes in a highly conservative industry.

化学制药行业正面临着前所未有的快速变化的环境，新的市场和技术趋势影响了公司的运营策略。因此，管理药品供应链（PSC）运营变得更加复杂和具有挑战性。这项工作的目的是全面概述行业的现状和研究发展；然后，开发新的决策参考框架，以帮助创建基于优化的决策支持模型。这将通过多角度分析来实现，该分析涵盖化学制药行业当前和未来的业务环境中的战略和战术计划决策。