In this issue of JAMA Psychiatry, DeRubeis et al¹ present the second phase of an elegantly designed study that has yielded results that will inform patient care and future research. A paucity of studies is available to inform the long-term treatment of persistent major depressive disorder (MDD), either chronic or recurrent.² Most studies have focused on short-term treatment with single interventions, and many longer-term studies have not been controlled.

中文翻译：

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持续性重度抑郁症患者康复后的预防复发-一项积极的追求。

在本期《JAMA精神病学》中，DeRubeis等人¹提出了一项精心设计的研究的第二阶段，该研究的结果将为患者护理和未来研究提供参考。目前尚缺乏足够的研究来告知长期或持续性持续性重度抑郁症（MDD）的长期治疗。²大多数研究都集中于单一干预的短期治疗，许多长期研究尚未得到控制。