BACKGROUND Prevention of antenatal and postnatal depression is crucial, given its high prevalence and severe consequences. Although several systematic reviews and meta-analyses have examined the effects of psychological interventions on the population at risk for perinatal depression, few studies have focused on universal prevention and none have focused specifically on universal prevention in pregnancy. The aim of this study is to examine the effects of psychological interventions with a universal prevention focus on perinatal depression during pregnancy by performing a systematic review and meta-analysis based on both the latest articles and a broader literature search. METHODS The literature search will be conducted using the Cochrane Controlled Register of Trials (CENTRAL), Embase, PubMed and PsycINFO, from inception onwards. Randomized controlled trials that examined the association between psychological interventions and universal prevention of antenatal and postnatal depression among pregnant women will be included. Study selection, data collection, quality assessment, and statistical syntheses will be conducted following a priori defined methods in the protocol. DISCUSSION The findings of this systematic review and meta-analysis will have both clinical and political importance in the context of perinatal mental health. In addition, this study will promote future studies and clarify the direction of research on universal prevention of perinatal depression. SYSTEMATIC REVIEW REGISTRATION PROSPERO CRD42019118041.

中文翻译：

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普遍预防孕妇产前和产后抑郁的心理干预：系统评价和荟萃分析的方案。

背景技术鉴于其高发和严重后果，预防产前和产后抑郁至关重要。尽管一些系统的评论和荟萃分析检查了心理干预措施对处于围生期抑郁风险中的人群的影响，但很少有研究侧重于普遍预防，而没有一项研究专门针对孕期普遍预防。这项研究的目的是通过对最新文章和更广泛的文献检索进行系统的综述和荟萃分析，以全面关注预防妊娠期围产期抑郁的心理干预措施的效果。方法从开始就使用Cochrane对照试验注册资料库（CENTRAL），Embase，PubMed和PsycINFO进行文献检索。将包括随机对照试验，该试验研究了心理干预与孕妇预防产前和产后抑郁的普遍预防之间的关系。研究方案的选择，数据收集，质量评估和统计综合将按照方案中的先验定义方法进行。讨论在围生期心理健康的背景下，这项系统评价和荟萃分析的结果将具有临床和政治意义。此外，这项研究将促进未来的研究，并阐明普遍预防围产期抑郁症的研究方向。系统审查注册PROSPERO CRD42019118041。