APP-derived peptides reflect neurodegeneration in frontotemporal dementia.,Annals of Clinical and Translational Neurology

当前位置： X-MOL 学术 › Ann. Clin. Transl. Neur. › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

APP-derived peptides reflect neurodegeneration in frontotemporal dementia.
Annals of Clinical and Translational Neurology ( IF 5.3 ) Pub Date : 2019-12-02 , DOI: 10.1002/acn3.50948
Ignacio Illán-Gala _{1,

2} , Jordi Pegueroles _{1,

2} , Victor Montal _{1,

2} , Daniel Alcolea _{1,

2} , Eduard Vilaplana _{1,

2} , Alexandre Bejanin _{1,

2} , Sergi Borrego-Écija ₃ , Frederic Sampedro ₄ , Andrea Subirana ₁ , María-Belén Sánchez-Saudinós ₁ , Ricard Rojas-García ₅ , Hugo Vanderstichele ₆ , Rafael Blesa _{1,

2} , Jordi Clarimón _{1,

2} , Anna Antonell ₃ , Albert Lladó ₃ , Raquel Sánchez-Valle ₃ , Juan Fortea _{1,

2,

7} , Alberto Lleó _{1,

2}

Affiliation

We aimed to investigate the relationship between cerebrospinal fluid levels (CSF) of amyloid precursor protein (APP)‐derived peptides related to the amyloidogenic pathway, cortical thickness, neuropsychological performance, and cortical gene expression profiles in frontotemporal lobar degeneration (FTLD)‐related syndromes, Alzheimer’s disease (AD), and healthy controls.

中文翻译：