Immunotherapy has shown remarkable successes in several tumor types and is now the first-line treatment for several conditions, including recurring disease. Nonetheless, a large fraction of patients does not respond, which is particularly true in glioblastoma. The results of Lee-Chang and colleagues point to intratumoral B cells as a potential target for immunotherapy.See article by Lee-Chang et al., p. 1928.

中文翻译：

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胶质母细胞瘤中位置依赖的B细胞功能。

免疫疗法已在多种肿瘤类型中取得了显著成功，现已成为包括复发性疾病在内的多种疾病的一线治疗方法。尽管如此，仍有很大一部分患者没有反应，这在胶质母细胞瘤中尤为明显。Lee-Chang及其同事的研究结果表明，肿瘤内B细胞可能成为免疫治疗的潜在靶标。1928年。