Aggregation-induced emission luminogens (AIEgens) with a large electron donor and acceptor (D–A) conjugated system have been widely used in the development of organic light emitting diodes (OLEDs), chemosensors, and bioimaging materials due to their excellent properties such as high quantum yields, long emission wavelengths, controllable luminescence lifetimes, and nonlinear optics (NLO) properties. However, most of the AIE materials have been derived from limited classic AIE cores such as tetraphenylethene (TPE) and tetraphenylpyrazine (TPP), and thus, tedious syntheses or later modifications toward those AIEgens have always been unavoidable. In this report, a type of atypical AIEgens (designated as ASIQs) composed of large conjugated structures with a natural electron D–A system is disclosed, which shows large Stokes shifts, high photostabilities, excellent cell permeabilities, low biotoxicities, and good two-photon excited capacities, making them suitable for applications of one-photon/two-photon targeted imaging in live cells. In short, this work offers a type of atypical AIEgens which will possibly become an ideal platform leading to more structurally diverse and functionally excellent AIE-based luminescent materials.

中文翻译：

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一种用于活细胞中单光子/双光子靶向成像的非典型 AIEgen

具有大电子供体和受体 (D-A) 共轭体系的聚集诱导发射发光材料 (AIEgens) 由于其优异的性能如高量子产率、长发射波长、可控发光寿命和非线性光学 (NLO) 特性。然而，大多数 AIE 材料来源于有限的经典 AIE 核，例如四苯基乙烯 (TPE) 和四苯基吡嗪 (TPP)，因此，对这些 AIEgens 进行繁琐的合成或后期修改一直是不可避免的。在本报告中，公开了一种由具有天然电子 D-A 系统的大型共轭结构组成的非典型 AIEgen（称为 ASIQ），它显示出大的斯托克斯位移，高光稳定性、优异的细胞渗透性、低生物毒性和良好的双光子激发能力，使其适用于活细胞中的单光子/双光子靶向成像应用。简而言之，这项工作提供了一种非典型的 AIEgens，它可能成为一个理想的平台，从而导致结构更加多样化和功能更加出色的 AIE 基发光材料。