The iridium‐catalyzed cycloisomerization of various alkynoic acids was successfully developed, and a series of five‐, six‐, and especially seven‐membered unsaturated lactones were constructed with moderate yields and excellent regioselectivities (up to 68% yield, >99:1 rr). In addition, the indole compound can be easily prepared with 75% yield through this efficient synthetic methodology. Moreover, a plausible mechanism for this Ir‐catalyzed cycloisomerization of alkynoic acids was proposed.

中文翻译：

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铱催化炔酸的环异构化：不饱和内酯的合成

各种炔酸的铱催化环异构化成功开发，并以中等收率和优异的区域选择性（高达68％收率，> 99：1 rr）构建了一系列五，六，尤其是七元不饱和内酯。 ）。另外，通过这种有效的合成方法，可以容易地以75％的产率制备吲哚化合物。此外，提出了这种Ir催化的炔酸环异构化的合理机理。