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Exploiting C–H borylation for the multidirectional elaboration of 2-halopyridines
Tetrahedron ( IF 2.1 ) Pub Date : 2019-11-29 , DOI: 10.1016/j.tet.2019.130836
Jonathan A. Reuven , Omar A. Salih , Scott A. Sadler , Carys L. Thomas , Patrick G. Steel

Regioselectively polysubstituted pyridines can be efficiently accessed from 2-halopyridines via a sequence involving C–H borylation, Suzuki-Miyaura cross-coupling and nucleophilic aromatic substitution chemistry.



中文翻译:

利用C–H硼化技术进行2-卤代吡啶的多向修饰

区域选择性多取代的吡啶可通过涉及C–H硼化,Suzuki-Miyaura交叉偶联和亲核芳香族取代化学的序列从2-卤代吡啶中高效地获得。

更新日期:2019-11-30
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