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Association of Hepatic Global DNA Methylation and Serum One-Carbon Metabolites with Histological Severity in Patients with NAFLD.
Obesity ( IF 6.9 ) Pub Date : 2019-11-29 , DOI: 10.1002/oby.22667 Zhiwei Lai 1 , Junliang Chen 1 , Chenghe Ding 1 , Kwanshu Wong 1 , Xingyi Chen 1 , Liuzhen Pu 1 , Qiangwei Huang 1 , Xiaolin Chen 1 , Zijian Cheng 1 , Yan Liu 2 , Xuying Tan 3 , Huilian Zhu 3 , Lijun Wang 1
Obesity ( IF 6.9 ) Pub Date : 2019-11-29 , DOI: 10.1002/oby.22667 Zhiwei Lai 1 , Junliang Chen 1 , Chenghe Ding 1 , Kwanshu Wong 1 , Xingyi Chen 1 , Liuzhen Pu 1 , Qiangwei Huang 1 , Xiaolin Chen 1 , Zijian Cheng 1 , Yan Liu 2 , Xuying Tan 3 , Huilian Zhu 3 , Lijun Wang 1
Affiliation
Clinical relevance of global DNA methylation and one‐carbon metabolite levels with histological severity remains uncertain in patients with nonalcoholic fatty liver disease (NAFLD). This study aimed to evaluate hepatic global DNA methylation and serum one‐carbon metabolite concentrations in patients with NAFLD and the possible associations of these parameters with liver histology.
中文翻译：
肝总DNA甲基化和血清一碳代谢产物与NAFLD患者组织学严重程度的关系。
非酒精性脂肪性肝病（NAFLD）患者中总体DNA甲基化和一碳代谢物水平与组织学严重程度的临床相关性仍不确定。这项研究旨在评估NAFLD患者的肝脏总体DNA甲基化和血清一碳代谢物浓度，以及这些参数与肝脏组织学的可能联系。
更新日期：2019-11-29
中文翻译：
肝总DNA甲基化和血清一碳代谢产物与NAFLD患者组织学严重程度的关系。
非酒精性脂肪性肝病（NAFLD）患者中总体DNA甲基化和一碳代谢物水平与组织学严重程度的临床相关性仍不确定。这项研究旨在评估NAFLD患者的肝脏总体DNA甲基化和血清一碳代谢物浓度，以及这些参数与肝脏组织学的可能联系。
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