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Targeting macrophage immunometabolism to prevent atherosclerosis.
Nature Metabolism ( IF 20.8 ) Pub Date : 2019-11-29 , DOI: 10.1038/s42255-019-0154-4
Luke A J O'Neill 1
Affiliation  

Di Gioia and colleagues report on how the oxidized phospholipid oxPAPC alters metabolism in macrophages via glutamine and oxaloacetate, thus boosting production of the cytokine IL-1β and promoting atherosclerosis.

中文翻译:

靶向巨噬细胞免疫代谢,以预防动脉粥样硬化。

Di Gioia及其同事报道了氧化磷脂oxPAPC如何通过谷氨酰胺和草酰乙酸改变巨噬细胞的代谢,从而促进细胞因子IL-1β的产生并促进动脉粥样硬化。
更新日期:2019-11-30
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