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Vagal nerve stimulation as a promising tool in the improvement of cognitive disorders.
Brain Research Bulletin ( IF 3.8 ) Pub Date : 2019-11-29 , DOI: 10.1016/j.brainresbull.2019.11.011
A Broncel 1 , R Bocian 2 , P Kłos-Wojtczak 1 , K Kulbat-Warycha 1 , J Konopacki 2
Affiliation  

Vagal nerve stimulation (VNS) is known as an effective method of treatment in a number of neurological disorders. The low risk of side effects also makes it useful in clinical trials in other diseases. Branches of the vagal nerve innervate the anatomical structures known to be involved in memory processing. That is why it seems justified that several studies emphasize the impact of VNS on the cognitive and memory function in both healthy volunteers and patients with epilepsy and Alzheimer's disease. Results have shown that VNS can modulate different types of memory depending the protocol of stimulation in non-demented patients after both short term and chronic VNS application. Transcutaneous vagal nerve stimulation (tVNS), which is a non-invasive method of VNS, opens up new perspectives for different clinical applications.

中文翻译:

迷走神经刺激作为改善认知障碍的有前途的工具。

迷走神经刺激(VNS)是许多神经系统疾病的有效治疗方法。副作用的低风险也使其可用于其他疾病的临床试验。迷走神经的分支支配着已知参与记忆处理的解剖结构。这就是为什么似乎有道理的是,有几项研究强调了VNS对健康志愿者以及癫痫和阿尔茨海默氏病患者的认知和记忆功能的影响。结果表明,短期和长期应用VNS后,VNS可以根据非痴呆患者的刺激方案来调节不同类型的记忆。经皮迷走神经刺激(tVNS)是VNS的一种非侵入性方法,为不同的临床应用开辟了新的前景。
更新日期:2019-11-30
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