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Are depression and anxiety disorders associated with adductor pollicis muscle thickness, sleep duration, and protein intake in cancer patients?
Experimental Gerontology ( IF 3.9 ) Pub Date : 2019-11-30 , DOI: 10.1016/j.exger.2019.110803
Débora E de Sousa 1 , Millena N de Carli 1 , Renata C Fernandes 1 , Daniella B Trindade 1 , Alessandro Laviano 2 , Claude Pichard 3 , Gustavo D Pimentel 1
Affiliation  

INTRODUCTION Psychological disturbances may be associated with compromised body composition and food intake. However, this has not been elucidated totally. Thus, this study aimed to evaluate the prevalence of anxiety and depression, and whether there is an association between these disorders and adductor pollicis muscle thickness (APMT), protein intake and sleep duration, in gastrointestinal cancer patients. METHODS A cross-sectional study evaluated 117 patients of both genders diagnosed with gastrointestinal cancer. Protein intake was assessed by the USDA food database; sleep duration by self-administered questionnaire; and APMT using the skinfold. The Hospital Anxiety and Depression Scale (HADS) was used to measure anxiety (HADS-A) and depression (HADS-D). RESULTS A total of 117 (65% male) patients were assessed, of which 40 (34%) had anxiety and 39 (33%) depression. There was a negative correlation between APMT and anxiety (r = -0.20, p = .020) and depression (r = -0.19, p = .03), and between anxiety and sleep duration (r = -0.30, p = .001). Although there was an inverse association between anxiety and APMT (OR: 0.88, 95%CI: 0.79-0.99, p = .032) and sleep duration (OR: 0.71, 95%CI: 0.58-0.87, p = .001), when adjusted for gender and age, the association remained only between anxiety and sleep duration (OR: 0.71, 95%CI: 0.58-0.87, p = .001). CONCLUSION One-third of gastrointestinal cancer patients were classified as expressing anxiety and depression. Additionally, only sleep duration is associated with anxiety.

中文翻译:

癌症患者的抑郁症和焦虑症是否与内收肌弯曲厚度,睡眠时间和蛋白质摄入有关?

引言心理障碍可能与身体成分和食物摄入受损有关。但是,这还没有完全阐明。因此,本研究旨在评估胃肠道癌患者焦虑和抑郁的患病率,以及这些疾病与内收肌政治厚度,APMT,蛋白质摄入和睡眠时间之间是否存在关联。方法一项横断面研究评估了117名诊断为胃肠道癌的男女患者。蛋白质摄入量由美国农业部食品数据库评估;自我管理问卷调查睡眠时间;以及使用皮褶的APMT。医院焦虑和抑郁量表(HADS)用于测量焦虑(HADS-A)和抑郁(HADS-D)。结果总共评估了117名患者(男性占65%),其中40名(34%)患有焦虑症,39名(33%)患有抑郁症。APMT与焦虑(r = -0.20,p = .020)和抑郁症(r = -0.19,p = .03)之间以及焦虑与睡眠时间之间存在负相关(r = -0.30,p = .001) )。尽管焦虑和APMT(OR:0.88,95%CI:0.79-0.99,p = .032)与睡眠时间之间呈负相关(OR:0.71,95%CI:0.58-0.87,p = .001),如果根据性别和年龄进行调整,则仅在焦虑与睡眠时间之间存在关联(OR:0.71,95%CI:0.58-0.87,p = .001)。结论胃肠道癌患者的三分之一被归类为焦虑和抑郁。另外,只有睡眠时间与焦虑有关。在焦虑和睡眠时间之间(r = -0.30,p = .001)。尽管焦虑和APMT(OR:0.88,95%CI:0.79-0.99,p = .032)与睡眠时间之间呈负相关(OR:0.71,95%CI:0.58-0.87,p = .001),如果根据性别和年龄进行调整,则仅在焦虑与睡眠时间之间存在关联(OR:0.71,95%CI:0.58-0.87,p = .001)。结论胃肠道癌患者的三分之一被归类为焦虑和抑郁。另外,只有睡眠时间与焦虑有关。在焦虑和睡眠时间之间(r = -0.30,p = .001)。尽管焦虑和APMT(OR:0.88,95%CI:0.79-0.99,p = .032)与睡眠时间之间呈负相关(OR:0.71,95%CI:0.58-0.87,p = .001),如果按性别和年龄进行调整,则仅在焦虑与睡眠时间之间存在关联(OR:0.71,95%CI:0.58-0.87,p = .001)。结论胃肠道癌患者的三分之一被归类为焦虑和抑郁。另外,只有睡眠时间与焦虑有关。相关性仅存在于焦虑和睡眠时间之间(OR:0.71,95%CI:0.58-0.87,p = .001)。结论胃肠道癌患者的三分之一被归类为焦虑和抑郁。另外,只有睡眠时间与焦虑有关。相关性仅存在于焦虑和睡眠时间之间(OR:0.71,95%CI:0.58-0.87,p = .001)。结论胃肠道癌患者的三分之一被归类为焦虑和抑郁。另外,只有睡眠时间与焦虑有关。
更新日期:2019-11-30
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