The functionalization and application of nano-objects generated using a polymerization induced self-assembly (PISA) procedure is becoming a focus in recent years. In this contribution, using ethanol as solvent, poly(oligo(ethylene oxide) methyl ether methacrylate) (POEOMA) as macro-initiator/stabilizer, and 2-(perfluorohexyl)ethyl methacrylate (PFHEMA) and glycidyl methacrylate (GMA) as comonomers, the initiators for continuous activator regeneration atom transfer radical polymerization (ICAR ATRP)-based PISA is realized. The lower GMA content system tends to form spheres with large diameters and heavy contrast, while the lower PFHEMA content system tends to form the spheres or short worms with small diameters. However, the system with further increased GMA content results in the failed ICAR ATRP PISA procedure with the formation of precipitates by the cross-linking reaction between pendant epoxy groups. Furthermore, using the efficient reaction between the epoxy group on GMA and thiol group on mercapto-succinic acid agent, the carboxyl groups can be introduced into the inner cavity of the nano-objects and used for incorporation with the Fe2+ and Fe3+ ions, and the organic-inorganic nanoparticles Fe3 O4 @POEOMA are finally prepared in the presence of a reductant.

中文翻译：

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基于ICAR ATRP的聚合诱导自组装技术的发展及其在有机无机纳米粒子制备中的应用。

近年来，利用聚合诱导自组装（PISA）程序生成的纳米物体的功能化和应用成为人们关注的焦点。在此贡献中，使用乙醇作为溶剂，使用聚（低聚（环氧乙烷）甲基丙烯酸甲基醚）（POEOMA）作为大分子引发剂/稳定剂，使用甲基丙烯酸2-（全氟己基）乙酯（PFHEMA）和甲基丙烯酸缩水甘油酯（GMA）作为共聚单体，实现了基于连续活化剂再生原子转移自由基聚合（ICAR ATRP）的PISA的引发剂。较低的GMA含量体系倾向于形成大直径和高对比度的球体，而较低的PFHEMA含量体系倾向于形成小直径的球体或短虫。然而，GMA含量进一步增加的系统会导致ICAR ATRP PISA程序失败，并通过环氧基侧基之间的交联反应形成沉淀。此外，利用GMA上的环氧基与巯基琥珀酸剂上的硫醇基之间的有效反应，可将羧基引入纳米物体的内腔中，并用于与Fe2 +和Fe3 +离子结合，以及最后在还原剂的存在下制备有机-无机纳米粒子Fe3O4 @ POEOMA。