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Self‐Moisturizing Smart Contact Lens Employing Electroosmosis
Advanced Materials Technologies ( IF 6.8 ) Pub Date : 2019-11-28 , DOI: 10.1002/admt.201900889
Shinya Kusama 1 , Kaito Sato 1 , Shotaro Yoshida 1 , Matsuhiko Nishizawa 1
Affiliation  

Contact lenses (CLs) can be a cause of “dry eye syndrome” that can lead to corneal wounds and inflammation as well as a feeling of discomfort. To prevent the dry eye, it is important to keep the lens moist and maintain tears between the CL and the ocular surface. Here, the use of electroosmotic flow (EOF) in a CL is reported as a novel mechanism for antidehydration. A CL made from a charged hydrogel has served as the fluid conduit for EOF generation. The charge density of the gel is optimized by varying the composition ratio of anionic monomer having carboxyl group, by taking into account the efficiency of EOF generation and the mechanical strength of the hydrogels. By in situ monitoring of conductance and by microscope observations, it is successfully demonstrated that the upward EOF within CL is effective to maintain a moist lens. Biocompatible batteries (Mg/O2 battery and fructose/O2 enzymatic battery) are mounted on the CL to demonstrate the feasibility of a smart CL with a built‐in power source for EOF‐based self‐moisturization.

中文翻译:

采用电渗作用的自保湿智能隐形眼镜

隐形眼镜(CL)可能是“干眼症候群”的原因,可能导致角膜伤口,发炎以及不适感。为防止干眼,重要的是要保持镜片湿润并保持CL和眼表之间的泪水。在此,报道了在CL中使用电渗流(EOF)作为抗脱水的新机制。由带电水凝胶制成的CL用作EOF生成的流体导管。考虑到EOF产生的效率和水凝胶的机械强度,通过改变具有羧基的阴离子单体的组成比来优化凝胶的电荷密度。通过电导率的原位监测和显微镜观察,已成功证明CL内的向上EOF可有效保持湿润的晶状体。在CL上安装了2个电池和果糖/ O 2酶电池,以演示带有内置电源的智能CL在基于EOF的自我保湿方面的可行性。
更新日期:2020-01-13
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