Magnetic nanosensors have become attractive instruments for the diagnosis and treatment of different diseases. They represent an efficient carrier system in drug delivery or in transporting contrast agents. For such purposes, magnetic nanosensors are used in vivo (intracorporeal application). To remove specific compounds from blood, magnetic nanosensors act as elimination system, which represents an extracorporeal approach. This review discusses principles, advantages and risks on recent advances in the field of magnetic nanosensors. First, synthesis methods for magnetic nanosensors and possibilities for enhancement of biocompatibility with different coating materials are addressed. Then, attention is devoted to clinical applications, in which nanosensors are or may be used as carrier- and elimination systems in the near future. Finally, risk considerations and possible effects of nanomaterials are discussed when working towards clinical applications with magnetic nanosensors.

中文翻译：

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磁性颗粒作为纳米传感器的生化功能：我们将其实施到临床实践还有多远？

磁性纳米传感器已经成为用于诊断和治疗不同疾病的有吸引力的仪器。它们代表了药物输送或造影剂传输的有效载体系统。为此，在体内使用磁性纳米传感器（体内应用）。为了从血液中去除特定化合物，磁性纳米传感器充当了消除系统，这代表了一种体外方法。这篇评论讨论了磁性纳米传感器领域的最新进展的原理，优势和风险。首先，解决了磁性纳米传感器的合成方法以及增强与不同涂层材料的生物相容性的可能性。然后，注意力集中在临床应用上，其中纳米传感器在不久的将来被用作或可以被用作载流子和消除系统。最后，