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Nano-drug delivery systems in wound treatment and skin regeneration
Journal of Nanobiotechnology ( IF 10.2 ) Pub Date : 2019-07-10 , DOI: 10.1186/s12951-019-0514-y
Wei Wang , Kong-jun Lu , Chao-heng Yu , Qiao-ling Huang , Yong-Zhong Du

Skin damages are defined as one of most common lesions people suffer from, some of wounds are notoriously difficult to eradicate such as chronic wounds and deep burns. Existing wound therapies have been proved to be inadequate and far from satisfactory. The cutting-edge nanotechnology offers an unprecedented opportunity to revolutionize and invent new therapies or boost the effectiveness of current medical treatments. In particular, the nano-drug delivery systems anchor bioactive molecules to applied area, sustain the drug release and explicitly enhance the therapeutic efficacies of drugs, thus making a fine figure in field relevant to skin regeneration. This review summarized and discussed the current nano-drug delivery systems holding pivotal potential for wound healing and skin regeneration, with a special emphasis on liposomes, polymeric nanoparticles, inorganic nanoparticles, lipid nanoparticles, nanofibrous structures and nanohydrogel.

中文翻译:

用于伤口治疗和皮肤再生的纳米药物输送系统

皮肤损伤被定义为人们所遭受的最常见的损伤之一,众所周知,某些伤口难以根除,例如慢性伤口和深度烧伤。现有的伤口疗法已被证明是不足的并且远远不能令人满意。尖端的纳米技术为革新和发明新疗法或提高当前医疗效果提供了前所未有的机会。特别地,纳米药物递送系统将生物活性分子锚定到应用区域,维持药物释放并显着增强药物的治疗效果,从而在与皮肤再生有关的领域中取得了良好的地位。这篇评论总结并讨论了当前的纳米药物输送系统,该系统在伤口愈合和皮肤再生方面具有关键潜力,其中特别着重于脂质体,
更新日期:2019-07-10
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