Uterine leiomyomas are often discovered during early pregnancy and in most cases will have no effect on pregnancy outcomes. However, in rare cases uterine leiomyomas may lead to obstetric complications. The aim of the study was to evaluate rate of uterine leiomyoma growth in the 3 trimesters of pregnancy. We conducted a retrospective cohort study. Included were women who were diagnosed with uterine leiomyoma during pregnancy and had at least two sonographic measurements in different trimesters. Data regarding leiomyoma growth, recorded by ultrasound examination, during 1st 2nd and 3rd trimesters were collected from electronic patient records. Two-hundred forty-eight uterine leiomyomas were included in the study. Leiomyoma area increased substantially in size between the 1st and 2nd trimesters (54.5% ± 75.9%, p = .007) and to a lesser degree between the 2nd and 3rd trimesters (17.9% ± 59.7%, NS). Evaluation of the change in size throughout the pregnancy – between 1st and 3rd trimesters revealed a significant increase of 95.9% ± 191.3% (p < .001). There was no significant growth of the leiomyomas between the 2nd and 3rd trimesters. Uterine leiomyomas tend to grow substantially during the 1st trimester of pregnancy. This trend is attenuated later with minimal growth towards the end of gestation.

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妊娠期子宫平滑肌瘤的生长方式

子宫平滑肌瘤通常在怀孕初期发现，并且在大多数情况下不会对妊娠结局产生影响。但是，在极少数情况下，子宫平滑肌瘤可能会导致产科并发症。该研究的目的是评估妊娠三个月子宫平滑肌瘤的生长速度。我们进行了一项回顾性队列研究。其中包括在怀孕期间被诊断患有子宫平滑肌瘤并且在不同的三个月中至少进行了两次超声检查的妇女。从电子患者记录中收集第1、2和3个月中超声检查记录的关于平滑肌瘤生长的数据。这项研究包括了248个子宫平滑肌瘤。子宫肌瘤面积在第1和第2个中期之间显着增加（54.5％±75.9％，p =。007），并且在第二和第三三个月之间的偏爱程度较低（17.9％±59.7％，NS）。对整个妊娠期大小变化的评估–在第1至第3孕期之间，显着增加了95.9％±191.3％（p <.001）。在第三个和第三个三个月之间，平滑肌瘤没有明显的增长。子宫平滑肌瘤在妊娠的前三个月趋于大量生长。这种趋势后来在妊娠末期以最小的增长而减弱。子宫平滑肌瘤倾向于在妊娠的前三个月大量生长。这种趋势后来在妊娠末期以最小的增长而减弱。子宫平滑肌瘤倾向于在妊娠的前三个月大量生长。这种趋势后来在妊娠末期以最小的增长而减弱。