A persistent low-level elevation of serum human chorionic gonadotropin (hCG) without clinical or radiological evidence of pregnancy or tumors was recently defined as quiescent gestational trophoblastic disease (Q-GTD). Whether patients with Q-GTD should be treated or allowed to become pregnant remains unclear. We herein report a rare case of Q-GTD in which the hCG level spontaneously returned to normal after a successful pregnancy. The patient was a 37-year-old primigravida who presented with a persistent low-level elevation of hCG after uterine evacuation of a hydatidiform mole. There was no evidence of neoplasia in the uterus or distant metastasis. The low-level elevation of hCG persisted for at least 2 years but never exceeded 200 mIU/mL. The patient had a successful pregnancy at the age of 40 years. Interestingly, her hCG level subsequently normalized without chemotherapy. The present case may imply the safety and therapeutic effect of pregnancy in women with Q-GTD.

中文翻译：

---

妊娠后静止性滋养细胞疾病自发消退：一例报告

没有持续妊娠或肿瘤的临床或放射学证据的血清人绒毛膜促性腺激素（hCG）持续低水平升高，最近被定义为静态妊娠滋养细胞疾病（Q-GTD）。尚不清楚是否应该治疗或允许Q-GTD患者怀孕。我们在此报告了Q-GTD的罕见情况，其中成功怀孕后hCG水平自发恢复正常。该患者为37岁的初产妇，在子宫排泄葡萄胎后，其hCG持续低水平升高。没有证据表明子宫内有肿瘤或远处转移。hCG的低水平升高持续至少2年，但从未超过200 mIU / mL。该患者在40岁时成功怀孕。有趣的是，她的hCG水平随后无需化疗即可恢复正常。本病例可能暗示Q-GTD妇女妊娠的安全性和治疗作用。