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Outcomes of colorectal cancer surgery in the nonagenarians: 20-year result from a tertiary center.
BMC Surgery ( IF 1.9 ) Pub Date : 2019-10-28 , DOI: 10.1186/s12893-019-0623-4
Toi Yin Chan 1 , Chi Chung Foo 2 , Wai Lun Law 2 , Oswens Lo 1
Affiliation  

BACKGROUND There is a foreseeable trend that life expectancy is on the rise in many parts of the world. More and more patients will present with colorectal cancer at extreme old age and advanced age is a well-known risk factor for adverse outcomes after surgery. The aim of this study is to evaluate the outcomes of colorectal cancer surgery in patients aged 90 or above. METHOD A retrospective analysis of consecutive patients aged 90 or above who underwent operations for colorectal cancer between January 1996 and December 2015 was performed. The primary outcomes were the complications rate, 30-day and 180-day mortality rates. RESULTS A total of 57 patients were included in the analysis. The majority of them were women (64.9%). The median age was 92 years. Most of the surgery was of curative intent (77.2%), performed under elective setting (57.9%) and with open approach (78.9%). 36.8% of patients had postoperative complications, with pneumonia being the commonest. The 30-day and 180-day mortality rate was 7 and 31.6% respectively. History of ischemic heart disease and surgery under emergency setting were predictors of postoperative complications. Pneumonia, preoperative leukocytosis and Charlson comorbidity score ≥ 9 were predictors of 180-day mortality. The one and two-year survival rate for elective surgery was 69.7 and 54.5% respectively. CONCLUSION The outcomes of colorectal cancer surgery for nonagenarians could be favorable in a selected group of patients. Future study on better risk profiling and ways to improve outcomes is warranted.

中文翻译:

非高加纳人结直肠癌手术的结果:来自第三中心的20年结果。

背景技术可以预见的趋势是,在世界许多地方,预期寿命正在增加。越来越多的患者将在极端高龄时出现大肠癌,而高龄是众所周知的术后不良后果的危险因素。这项研究的目的是评估90岁或90岁以上患者结直肠癌手术的效果。方法对1996年1月至2015年12月间接受结直肠癌手术的90岁以上连续患者进行回顾性分析。主要结果是并发症发生率,30天和180天死亡率。结果分析共纳入57例患者。其中大多数是妇女(64.9%)。中位年龄为92岁。大多数手术是在选择性的情况下进行的,具有治愈意图(77.2%)(57。9%)和开放式(78.9%)。36.8%的患者术后并发症,其中以肺炎最为常见。30天和180天死亡率分别为7和31.6%。缺血性心脏病的病史和紧急情况下的手术是术后并发症的预测指标。肺炎,术前白细胞增多和Charlson合并症评分≥9是180天死亡率的预测指标。择期手术的一年和两年生存率分别为69.7和54.5%。结论非老年患者结直肠癌手术的结局在某些患者中可能是有利的。将来有必要进行更好的风险分析和改善结果的方法的研究。30天和180天死亡率分别为7和31.6%。缺血性心脏病的病史和紧急情况下的手术是术后并发症的预测指标。肺炎,术前白细胞增多和Charlson合并症评分≥9是180天死亡率的预测指标。择期手术的一年和两年生存率分别为69.7和54.5%。结论非老年患者结直肠癌手术的结局在某些患者中可能是有利的。将来有必要进行更好的风险分析和改善结果的方法的研究。30天和180天死亡率分别为7和31.6%。缺血性心脏病的病史和紧急情况下的手术是术后并发症的预测指标。肺炎,术前白细胞增多和Charlson合并症评分≥9是180天死亡率的预测指标。择期手术的一年和两年生存率分别为69.7和54.5%。结论非老年患者结直肠癌手术的结局在某些患者中可能是有利的。将来有必要进行更好的风险分析和改善结果的方法的研究。择期手术的一年和两年生存率分别为69.7和54.5%。结论非老年患者结直肠癌手术的结局在某些患者中可能是有利的。将来有必要进行更好的风险分析和改善结果的方法的研究。择期手术的一年和两年生存率分别为69.7和54.5%。结论对于非老年患者,结直肠癌手术的结果在选定的一组患者中可能是有利的。将来有必要进行更好的风险分析和改善结果的方法的研究。
更新日期:2019-10-28
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