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Kikuchi-Fujimoto disease: a case report and the evaluation of diagnostic procedures.
BMC Oral Health ( IF 2.9 ) Pub Date : 2019-10-21 , DOI: 10.1186/s12903-019-0920-4 Shenjie Xu 1 , Weilian Sun 1 , Jiamei Liu 1
BMC Oral Health ( IF 2.9 ) Pub Date : 2019-10-21 , DOI: 10.1186/s12903-019-0920-4 Shenjie Xu 1 , Weilian Sun 1 , Jiamei Liu 1
Affiliation
BACKGROUND
Kikuchi-Fujimoto disease, known as histiocytic necrotizing lymphadenitis, is a benign, self-limiting and systemic disorder involving lymph nodes with unknown aetiology. First reported in Japan, there has been an increase in its incidence globally. Because of its non-specific clinical features, the disease can be easily mistaken for other forms of lymphadenitis with a high rate of misdiagnosis and mistreatment, posing a considerable challenge.
CASE PRESENTATION
A case of young Chinese woman with fever and cervical lymphadenopathy is presented. Physical examinations and imaging techniques were used to rule out common forms of lymphadenitis (e.g. cat-scratch disease and tuberculous lymphadenitis). Laboratory tests were then conducted to exclude others such as systemic lupus erythematosus and non-Hodgkin lymphoma. After Kikuchi-Fujimoto disease was identified, the patient was managed with symptomatic treatments. Our case was compared with relevant cases in the literature. A diagnostic flow chart was proposed to facilitate the diagnosis and treatment.
CONCLUSIONS
With its shared clinical features, Kikuchi-Fujimoto disease can be mistaken for other forms of lymphadenitis. A combined use of medical imaging and laboratory tests is the effective way to avoid misdiagnosis.
更新日期：2019-11-28
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