当前位置: X-MOL 学术BMC Endocr. Disord. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Determinants of poor glycemic control among adult patients with type 2 diabetes mellitus in Jimma University Medical Center, Jimma zone, south west Ethiopia: a case control study.
BMC Endocrine Disorders ( IF 2.7 ) Pub Date : 2019-08-29 , DOI: 10.1186/s12902-019-0421-0
Yitagesu Mamo 1 , Fekede Bekele 2 , Tadesse Nigussie 3 , Ameha Zewudie 1
Affiliation  

OBJECTIVE AND BACKGROUND In 2015 approximately 5.0 million people were estimated to have died from diabetes. Poor glycemic control is the most determinant of diabetes-related complication and death. The percentage of patients whose blood glucose level are not well controlled remains high yet. The aim of this study is to identify the determinants of poor glycemic control at the diabetes clinic of the Jimma University Medical Center from April 01 to June 30/2017. METHODS Facility-based case-control study design was conducted on patients with type 2 diabetes mellitus on follow-up at the diabetes clinic of Jimma University medical center. The consecutive sampling technique was employed and data were collected from April to June 2017. The data were entered using Epidata manager version 4.0.2 and exported to SPSS Version 21 for analysis. Logistic regression analysis was performed and variables with the p-value of less than 0.05 were considered as statistically significant determinants of poor glycemic control. RESULT The study was conducted on 410 patients, of which 228 males and 182 females. The determinants of poor glycemic control were comorbidities [Adjusted odd ratio(AOR) = 2.56, 95%CI = 1.10-5.96], lack of self-monitoring blood glucose [AOR = 3.44,95%CI = 1.33-8.94], total cholesterol level of 200 mg/dl or more [AOR = 3.62, 95%CI = 1.46-8.97], diabetes duration of greater than 7 years [AOR = 3.08, 95%CI = 1.33-7.16], physical activity of three or less than three days [AOR = 4.79, 95%CI = 1.70-13.53], waist to hip ratio of 0.9 or greater for male and 0.85 or greater for female [AOR = 3.52, 95%CI = 1.23-10.11], being on metformin plus insulin [AOR = 9.22, 95%CI = 2.90-29.35] and being on insulin [AOR = 4.48, 95%CI = 1.52-13.16]. CONCLUSION Lack of Self-monitoring blood glucose, presence of comorbidities, duration of diabetes mellitus, physical activity of three or less than three days, total cholesterol of 200 mg/dl or more, waist to hip ratio of 0.9 or greater for male and 0.85 or greater for female, and types of antidiabetic medication were the independent predictors of poor glycemic control. Effort should be made towards reducing these factors by the concerned body.

中文翻译:

埃塞俄比亚西南部吉马地区吉马大学医学中心成年2型糖尿病患者血糖控制不佳的决定因素:一项病例对照研究。

目的和背景2015年,估计有500万人死于糖尿病。血糖控制不佳是糖尿病相关并发症和死亡的最主要决定因素。血糖水平未得到很好控制的患者比例仍然很高。这项研究的目的是确定2017年4月1日至2017年6月30日在吉马大学医学中心糖尿病诊所的血糖控制不佳的决定因素。方法在吉马大学医学中心糖尿病诊所对2型糖尿病患者进行基于设施的病例对照研究设计。采用了连续采样技术,并于2017年4月至2017年6月收集了数据。使用Epidata Manager 4.0.2版输入数据,并导出到SPSS 21版进行分析。进行逻辑回归分析,将p值小于0.05的变量视为血糖控制不良的统计学显着决定因素。结果本研究针对410例患者进行,其中男性228例,女性182例。血糖控制不良的决定因素是合并症[调整后的奇数比(AOR)= 2.56,95%CI = 1.10-5.96],缺乏自我监测血糖[AOR = 3.44,95%CI = 1.33-8.94],总胆固醇200 mg / dl或更高水平[AOR = 3.62,95%CI = 1.46-8.97],糖尿病持续时间大于7年[AOR = 3.08,95%CI = 1.33-7.16],身体活动度不超过3三天[AOR = 4.79,95%CI = 1.70-13.53],男性使用二甲双胍+,腰部与臀部的比例为男性为0.9或更高,女性为0.85或更高[AOR = 3.52,95%CI = 1.23-10.11]胰岛素[AOR = 9.22,95%CI = 2.90-29。35]并接受胰岛素治疗[AOR = 4.48,95%CI = 1.52-13.16]。结论缺乏自我监测血糖,合并症,糖尿病持续时间,三天或少于三天的体育锻炼,总胆固醇为200 mg / dl或以上,男性腰臀比为0.9或更高,男性为0.85大于或等于女性,并且抗糖尿病药物的类型是不良血糖控制的独立预测因子。有关机构应努力减少这些因素。抗糖尿病药物的种类和类型是血糖控制不良的独立预测因素。有关机构应努力减少这些因素。抗糖尿病药物的种类和类型是血糖控制不良的独立预测因素。有关机构应努力减少这些因素。
更新日期:2019-08-29
down
wechat
bug