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Addressing cardiometabolic risk in adults with spinal cord injury: acting now despite knowledge gaps.
Spinal Cord Series and Cases Pub Date : 2019-11-27 , DOI: 10.1038/s41394-019-0241-5
S Sabharwal 1, 2
Affiliation  

This perspective advocates for the adoption of recently published clinical practice guidelines on identifying and managing cardiometabolic risk after spinal cord injury (SCI). It makes the case for acting now, with the knowledge that we currently have, while continuing to address knowledge gaps with high-quality research studies in this area. Cardiovascular disease is a leading cause of death in people with SCI. Cardiometabolic disease (CMD) and risks are more likely to be overlooked after SCI. Unique SCI-related considerations impact both assessment and management of cardiometabolic risk. Risk factors and components of CMD including obesity, impaired glucose tolerance/insulin resistance, dyslipidemia, and hypertension should be evaluated and managed to optimize the cardiometabolic health of this population. While it would be optimal to base all care on high-quality evidence-based research, its absence should not be an excuse for inaction. Applying what is currently known and filling the research gaps with empirical recommendations based on clinical rationale and expert consensus is both appropriate and necessary till more definitive SCI-specific evidence becomes available.



中文翻译:

解决成人脊髓损伤的心脏代谢风险:尽管存在知识差距,但现在就采取行动。

这种观点主张采用最近发布的关于识别和管理脊髓损伤(SCI)后心脏代谢风险的临床实践指南。它提出了利用我们目前拥有的知识立即采取行动的理由,同时继续通过该领域的高质量研究来弥补知识差距。心血管疾病是 SCI 患者死亡的主要原因。SCI 后心脏代谢疾病 (CMD) 和风险更容易被忽视。与 SCI 相关的独特考虑因素会影响心脏代谢风险的评估和管理。应评估和管理 CMD 的危险因素和组成部分,包括肥胖、糖耐量受损/胰岛素抵抗、血脂异常和高血压,以优化该人群的心脏代谢健康。虽然最好将所有护理都建立在高质量的循证研究的基础上,但缺乏这一点不应成为不采取行动的借口。在获得更明确的 SCI 特异性证据之前,应用目前已知的知识并通过基于临床原理和专家共识的经验建议来填补研究空白​​既是适当的也是必要的。

更新日期:2019-11-27
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