This work proposes a correlation methodology for solubilities (w_i) of α-tocopherol and δ-tocopherol in supercritical CO₂, and reports new experimental data at (40, 50, 60) ºC and (9.8–33.6) MPa. The methodology is based on the Gibbs-Duhem test to assess thermodynamic consistency of isothermal solubilities, represented using the Peng-Robinson EoS + Wong-Sandler mixing rule. Chrastil’s model was best-fitted after discarding low-solubility outlier (non-represented by the EoS), high-solubility (>100 g/m³ solute/CO₂, CO₂ density modified by the solute), and thermodynamically inconsistent data. Additionally, the mean error of log(w_i) (with thresholds for data reported of ±0.21 for α-tocopherol, and ±0.27 for δ-tocopherol) and the average bias were computed to discard questionable data sources. α-Tocopherol solubility was 3-to-4 times lower than δ-tocopherol’s at equivalent system conditions. Their solubilities exhibited less dependency on system temperature and CO₂ density than reported in literature, possibly due to experimental difficulties in handling comparably high-solubility solutes (>0.5 × 10⁻³ mol/mol).

这项工作为α-生育酚和δ-生育酚在超临界CO _2中的溶解度（w _i）提出了一种相关方法，并报道了在（40，50，60）ºC和（9.8–33.6）MPa下的新实验数据。该方法基于Gibbs-Duhem检验来评估等温溶解度的热力学一致性，使用Peng-Robinson EoS + Wong-Sandler混合法则表示。在丢弃低溶解度离群值（未由EoS表示），高溶解度（> 100 g / m ³溶质/ CO ₂，由溶质改性的CO ₂密度）和热力学不一致的数据之后，Chrastil的模型最适合。另外，log（w _i的平均误差）（对于α-生育酚报告的数据阈值为±0.21，对于δ-生育酚的报告阈值为±0.27）和平均偏差被计算以丢弃可疑数据源。在等效系统条件下，α-生育酚的溶解度比δ-生育酚的溶解度低3-4倍。与文献报道相比，它们的溶解度对系统温度和CO ₂密度的依赖性较小，这可能是由于在处理相对较高的溶解性溶质（> 0.5×10 ^-3 mol / mol）方面存在实验困难。