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The emergence of subclades A1 and A3 avipoxviruses in India.
Transboundary and Emerging Diseases ( IF 4.3 ) Pub Date : 2019-11-23 , DOI: 10.1111/tbed.13413
Basanta Pravas Sahu 1 , Prativa Majee 1 , Chinmayee Mishra 2 , Manojita Dash 2 , Sangram Biswal 2 , Niranjan Sahoo 2 , Debasis Nayak 1
Affiliation  

During the years 2010-2018, avipoxvirus (APV) outbreaks were observed in the domestic chickens and pigeons present in the eastern Indian state of Odisha. Based on typical pox lesions, followed by molecular techniques, the overall morbidity was found to be 18%-19.23% and 16.92%-23% in chickens and pigeons, respectively. The cutaneous forms of the disease were observed with varied rates of mortality, being 47.36%-52.77% in chickens and 39.13%-92% in pigeons. PCR amplification targeting the viral P4b core protein-coding gene and the DNA polymerase gene confirmed the presence of APV strains in 10 birds. Subsequent phylogenetic analysis of these two genes confirmed that the circulating strains were members of APV clade A. The subclade analysis revealed the introduction of A1 and A3 subclades in Indian chickens and pigeons, respectively. This study is the first molecular record of APVs circulating in eastern Indian birds (Odisha) and involves the first use of the polymerase gene to reveal the circulating clades of Indian APVs.

中文翻译:

在印度出现了亚群A1和A3禽痘病毒。

在2010-2018年间,在印度东部奥里萨邦的家养鸡和鸽子中发现了禽痘病毒(APV)爆发。根据典型的痘病病灶,再通过分子技术,发现鸡和鸽子的总发病率分别为18%-19.23%和16.92%-23%。观察到该疾病的皮肤形式具有不同的死亡率,在鸡中为47.36%-52.77%,在鸽子中为39.13%-92%。以病毒P4b核心蛋白编码基因和DNA聚合酶基因为靶点的PCR扩增证实了10羽禽中APV株的存在。随后对这两个基因的系统发育分析证实,循环菌株是APV进化枝A的成员。子进化枝分析表明分别在印度鸡和鸽子中引入了A1和A3进化枝。
更新日期:2019-11-23
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