Anorexia nervosa (AN) is associated with multiple medical complications. One of the rare permanent complications of AN is the deleterious effect that it has on a patient's bone mineral density (BMD). We report on the Dual-Energy X-ray Absorptiometry (DXA) findings of 336 consecutive patients with AN. Also, we investigated the effects of different factors on these DXA results. These factors included age, body mass index (BMI), percentage of ideal body weight (IBW), duration of illness, duration of amenorrhea, medications such as proton pump inhibitors (PPI) or selective serotonin reuptake inhibitors (SSRI), tobacco use and 25-hydroxy vitamin D levels. This study demonstrated a concerning high prevalence of reduced bone mineral density in patients with AN. Thus, the implication being that those involved in the care of patients with AN need to be cognizant of this serious complication and not be assuaged by the young age of this patient population.

中文翻译：

---

大量神经性厌食症患者的骨密度状态

神经性厌食症 (AN) 与多种医学并发症有关。AN 罕见的永久性并发症之一是它对患者骨矿物质密度 (BMD) 的有害影响。我们报告了 336 名连续 AN 患者的双能 X 射线吸收测定 (DXA) 结果。此外，我们调查了不同因素对这些 DXA 结果的影响。这些因素包括年龄、体重指数 (BMI)、理想体重百分比 (IBW)、疾病持续时间、闭经持续时间、质子泵抑制剂 (PPI) 或选择性血清素再摄取抑制剂 (SSRI) 等药物、烟草使用和25-羟基维生素 D 水平。该研究表明，AN 患者骨矿物质密度降低的患病率很高。因此，