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Accuracy of transcutaneous bilirubin on covered skin in preterm and term newborns receiving phototherapy using a JM-105 bilirubinometer.
Journal of Perinatology ( IF 2.9 ) Pub Date : 2019-11-25 , DOI: 10.1038/s41372-019-0557-9
U Costa-Posada 1 , A Concheiro-Guisán 2 , M F Táboas-Ledo 2 , E González-Colmenero 2 , M L González-Durán 2 , M Suarez-Albo 2 , C Duran Fernández-Feijoo 2 , M Pumarada-Prieto 2 , Cristina Martínez-Reglero 3 , J R Fernández-Lorenzo 2
Affiliation  

OBJECTIVE Determine the suitability of transcutaneous bilirubin (TCB) as a tool to assess the effectiveness of phototherapy on patched skin. STUDY DESIGN A prospective observational study was conducted. We covered a fragment of skin (sternum) with a photo-opaque patch. Several simultaneous TCB and TSB measurements were performed with the JM-105 bilirubinometer. Bland and Altman test evaluated the agreement between bilirubin levels. RESULT A total of 217 patients were studied, 48.8% were preterm. The mean difference between TSB and TCB before the start of treatment was 1.07 mg/dL. During phototherapy, differences on covered skin were 0.52, 0.27, and 0.39 mg/dL at 24, 48, and 72 h of therapy respectively. The best correlation was observed at 48 h in preterm infants. CONCLUSION The measurement of TCB on patched skin (PTCB) is useful for monitoring the response to phototherapy in term and preterm infants. We use a patch with a removable flap that eases successive measures without disturbing the patients.

中文翻译:

使用JM-105胆红素计在接受光疗的早产和足月新生儿中经皮胆红素在覆盖皮肤上的准确性。

目的确定经皮胆红素(TCB)作为评估光疗对斑驳皮肤的有效性的工具的适用性。研究设计进行了一项前瞻性观察研究。我们用不透光的补丁覆盖了一块皮肤(胸骨)。使用JM-105胆红素计同时进行了几次TCB和TSB测量。Bland和Altman测试评估了胆红素水平之间的一致性。结果共研究了217例患者,其中48.8%为早产儿。开始治疗前,TSB和TCB的平均差为1.07 mg / dL。在光疗期间,在24、48和72小时的治疗后,覆盖皮肤的差异分别为0.52、0.27和0.39 mg / dL。早产儿在48 h观察到最佳相关性。结论斑贴皮肤(TCB)上TCB的测量可用于监测足月和早产儿对光疗的反应。我们使用带有可移动瓣的贴片,可轻松进行后续措施而不会打扰患者。
更新日期:2019-11-26
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