AIM To analyse post-transplant outcomes of NODAT patients in comparison to the regular cohort (non-NODAT). OBJECTIVES To compare graft survival and rejection rate, patient survival rate, incidence of hospitalization (due to any cause) in between NODAT and non-NODAT groups in cases of renal transplantation. METHODS A single-centred prospective real-world observational study of 100 subjects who underwent renal transplantation over a period of two years. All NODAT cases evaluated for graft survival/rejection, incidence of hospitalisation/infection, mortality from all causes and compared with that of non-NODAT post-transplant recipients. Nominal categorical data between the groups are compared using Chi-square test or Fisher's exact test as appropriate. p value < 0.05 was taken to indicate a significant difference. RESULTS Mean number of hospital admissions of subjects was 1.38 ± 1.38 and 0.29 ± 0.56 in NODAT and Non-NODAT respectively, p < 0.0001. Nineteen out of 24 NODAT subjects and 72 out of 76 Non-NODAT subjects had graft survival, p = 0.0342. Twenty out of 24 NODAT and 74 out of 76 Non-NODAT subjects had survived, p = 0.0282. CONCLUSIONS NODAT leads to adverse outcomes viz. increased rate of hospitalization, reduced rates of allograft survival and patient survival.

中文翻译：

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一项前瞻性观察性研究在印度东部的一家三级医疗中心评估了肾移植术后新发糖尿病的结局（NODAT）。

目的与常规队列（非NODAT）相比，分析NODAT患者的移植后结局。目的比较肾移植患者在NODAT组和非NODAT组之间的移植物存活率和排斥率，患者存活率，住院发生率（由于任何原因）。方法对100名在两年内进行了肾脏移植的受试者进行了单中心前瞻性现实世界观察性研究。所有NODAT病例均评估了移植物存活/排斥，住院/感染发生率，各种原因的死亡率，并与非NODAT移植后接受者进行了比较。使用卡方检验或Fisher精确检验比较组之间的名义分类数据。p值<0.05表明存在显着差异。结果NODAT和Non-NODAT患者的平均入院人数分别为1.38±1.38和0.29±0.56，p <0.0001。24名NODAT受试者中的19名和76名非NODAT受试者中的72名具有移植物存活率，p = 0.0342。24名NODAT患者中有20名幸存，而76名非NODAT患者中有74名幸存下来，p = 0.0282。结论NODAT导致不良结局，即。增加住院率，降低同种异体移植存活率和患者存活率。