The effectiveness of antiretroviral therapy and its increasing availability globally means that millions of people living with HIV now have a much longer life expectancy. However, people living with HIV have disproportionately high incidence of major comorbidities and reduced health-related quality of life. Health systems must respond to this situation by pioneering care and service delivery models that promote wellness rather than mere survival. In this Series paper, we review evidence about the emerging challenges of the care of people with HIV beyond viral suppression and identify four priority areas for action: integrating HIV services and non-HIV services, reducing HIV-related discrimination in health-care settings, identifying indicators to monitor health systems' progress toward new goals, and catalysing new forms of civil society engagement in the more broadly focused HIV response that is now needed worldwide. Furthermore, in the context of an increasing burden of chronic diseases, we must consider the shift that is underway in the HIV field in relation to burgeoning policy and programmatic efforts to promote healthy ageing.

抗逆转录病毒疗法的有效性及其在全球范围内的日益普及，意味着数百万艾滋病毒携带者现在的预期寿命更长。但是，艾滋病毒感染者的主要合并症发病率高得不成比例，与健康相关的生活质量下降。卫生系统必须通过开创促进健康而不是单纯生存的护理和服务提供模式来应对这种情况。在本系列文章中，我们回顾了有关病毒抑制之外的艾滋病病毒感染者的新挑战的证据，并确定了四个优先行动领域：整合艾滋病毒服务和非艾滋病毒服务，减少医疗机构中与艾滋病毒相关的歧视，确定指标以监控卫生系统向新目标的进展，并促使民间社会以新形式参与更广泛关注的艾滋病应对工作，而这在当今世界范围内是必需的。此外，在慢性病负担日益增加的背景下，我们必须考虑艾滋病毒领域正在发生的与为促进健康老龄化而迅速发展的政策和方案性努力有关的转变。