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A randomised assessment of image guided radiotherapy within a phase 3 trial of conventional or hypofractionated high dose intensity modulated radiotherapy for prostate cancer
Radiotherapy and Oncology ( IF 5.7 ) Pub Date : 2020-01-01 , DOI: 10.1016/j.radonc.2019.10.017
Julia Murray 1 , Clare Griffin 2 , Sarah Gulliford 3 , Isabel Syndikus 4 , John Staffurth 5 , Miguel Panades 6 , Christopher Scrase 7 , Chris Parker 1 , Vincent Khoo 1 , Jamie Dean 2 , Helen Mayles 4 , Philip Mayles 4 , Simon Thomas 8 , Olivia Naismith 9 , Angela Baker 10 , Helen Mossop 2 , Clare Cruickshank 2 , Emma Hall 2 , David Dearnaley 1 ,
Affiliation  

Highlights • Introduction of daily online prostate IGRT was feasible in a national randomised trial.• Dosimetric benefits seen in patients treated with IGRT and reduced CTV-PTV margins.• Overall side effect profiles were acceptable in all groups but lowest with IGRT and reduced margins.

中文翻译:

前列腺癌常规或大分割高剂量调强放疗 3 期试验中影像引导放疗的随机评估

要点 • 在全国随机试验中引入每日在线前列腺 IGRT 是可行的。• 在接受 IGRT 治疗的患者中观察到剂量学益处并降低 CTV-PTV 边缘。• 所有组的总体副作用概况均可接受,但 IGRT 和边缘减少的副作用最低。
更新日期:2020-01-01
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