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Endurance training improves plasma superoxide dismutase activity in healthy elderly.
Mechanisms of Ageing and Development ( IF 5.3 ) Pub Date : 2019-11-22 , DOI: 10.1016/j.mad.2019.111190
Roberta Ceci 1 , Guglielmo Duranti 1 , Ester Sara Di Filippo 2 , Danilo Bondi 2 , Vittore Verratti 3 , Christian Doria 2 , Daniela Caporossi 1 , Stefania Sabatini 1 , Ivan Dimauro 1 , Tiziana Pietrangelo 2
Affiliation  

We aimed to characterize the plasma redox homeostasis as underlying physiological mechanisms of specific training on healthy elderly. 51 healthy volunteers were trained to endurance, resistance, Neuro-Muscular Electrical Stimulation for 12 weeks, 3 sessions/w, all applied to lower limbs. We assessed ex-post quadriceps' maximal voluntary contraction, handgrip strength, five-times-sit to stand and timed up-and-go tests, oxidative damage (lipid peroxidation, protein carbonyl groups), antioxidant enzyme activities (superoxide dismutase, Catalase, Glutathione peroxidase, Glutathione homeostasis), free thiols and total antioxidant status. We found significant difference in ex-post × protocol and in post-hoc analysis specifically for plasma superoxide dismutase activity in endurance training.

中文翻译:

耐力训练可改善健康老年人的血浆超氧化物歧化酶活性。

我们旨在将血浆氧化还原稳态定性为健康老年人特定训练的潜在生理机制。对51名健康志愿者进行了耐力,抵抗力,神经肌肉电刺激训练,为期12周,3次/ w,均适用于下肢。我们评估了股四头肌的最大自愿收缩力,握力,五次站立和定时向上移动测试,氧化损伤(脂质过氧化,蛋白羰基),抗氧化酶活性(超氧化物歧化酶,过氧化氢酶,谷胱甘肽过氧化物酶,谷胱甘肽稳态),游离硫醇和总抗氧化剂状态。我们发现在事后×协议和专门用于血浆超氧化物歧化酶活性的事后分析中,在耐力训练中存在显着差异。
更新日期:2019-11-22
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