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A Small-Molecule Drug Targeting STAT3 Causes Tumor Regression in Mice.
Cancer Discovery ( IF 28.2 ) Pub Date : 2020-01-01 , DOI: 10.1158/2159-8290.cd-rw2019-175
American Association for Cancer Research

SD-36, a small-molecule proteolysis-targeting chimera (PROTAC), causes STAT3 degradation in vivo.

中文翻译:

一种靶向 STAT3 的小分子药物导致小鼠肿瘤消退。

SD-36 是一种小分子蛋白水解靶向嵌合体 (PROTAC),可导致体内 STAT3 降解。
更新日期:2020-04-21
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