Hypertension (HTN) is a major modifiable risk factor for cardiovascular disease (CVD) morbidity and mortality. The left ventricle (LV) is a primary target for HTN end-organ damage. In addition to being a marker of HTN, LV geometrical changes: concentric remodeling, concentric or eccentric LV hypertrophy (LVH) are major independent risk factors for not only CVD morbidity and mortality but also for all-cause mortality and neurological pathologies. Blood pressure control with lifestyle changes and antihypertensive agents has been demonstrated to prevent and regress LVH. Herein, we provide a comprehensive review of literature on the relationship between HTN and LV geometry abnormalities with a focus on diagnosis, prognosis, pathophysiological mechanisms, and treatment approaches.

中文翻译：

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左心室肥厚和高血压。

高血压 (HTN) 是心血管疾病 (CVD) 发病率和死亡率的主要可改变危险因素。左心室 (LV) 是 HTN 终末器官损伤的主要目标。除了作为 HTN 的标志物之外，LV 几何变化：同心重塑、同心或偏心 LV 肥大 (LVH) 不仅是 CVD 发病率和死亡率的主要独立危险因素，也是全因死亡率和神经病理学的主要独立危险因素。已经证明通过改变生活方式和服用抗高血压药物控制血压可以预防和缓解 LVH。在此，我们全面回顾了 HTN 与 LV 几何异常之间关系的文献，重点是诊断、预后、病理生理机制和治疗方法。