Allogeneic hematopoietic cell transplantation (HCT) is a demanding treatment with well-established medical and psychosocial sequelae. Impacts on significant others are tremendous. Using an unfiltered qualitative approach, we asked spouses (n = 15) of HCT recipients to talk about their thoughts and feelings regarding the transplantation and their role as caregiver. Recordings were transcribed and independently coded to identify recurrent patterns. Caregivers mentioned both negative and positive psychological impacts of HCT, but the number of negative impacts was greater: 164 versus 34 instances. The most frequently mentioned negative psychological impacts were anxiety/worry (30 instances), fear (20 instances), feeling overloaded/overwhelmed (19 instances), and uncertainty (17 instances). Other emergent categories were roles/responsibilities (49 instances) such as parenting, work, and treatment-related tasks, and coping strategies (55 instances). The latter included both adaptive and maladaptive strategies (75% and 25%, respectively). Despite the preponderance of negatively toned thoughts and feelings, signs of adjustment emerged, with mentions of positive psychological states, such as optimism and gratitude, and adaptive coping strategies, such as active coping, use of emotional support, and self-care. Interventions intended to facilitate adaptation to the HCT experience should involve strategies to help caregivers manage symptoms of distress and promote adaptive coping.

中文翻译：

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造血细胞移植受者的配偶照顾者报告的心理影响和应对方式：定性分析。

同种异体造血细胞移植（HCT）是一项要求严格的治疗，具有成熟的医学和社会心理后遗症。对重大他人的影响是巨大的。我们使用未经过滤的定性方法，让HCT接受者的配偶（n = 15）谈论他们关于移植的想法和感受以及他们作为照料者的作用。记录被转录并独立编码以识别重复出现的模式。护理人员提到了HCT对心理的负面和正面影响，但负面影响的数量更多：分别为164和34。最常提及的负面心理影响是焦虑/担忧（30例），恐惧（20例），感觉超负荷/不堪重负（19例）和不确定性（17例）。其他紧急情况类别包括角色/职责（49个实例），例如育儿，工作和与治疗相关的任务以及应对策略（55个实例）。后者包括适应性策略和适应不良的策略（分别为75％和25％）。尽管消极的思想和情绪占主导地位，但还是出现了适应的迹象，其中提到了积极的心理状态，例如乐观和感激之情，以及适应性应对策略，例如积极应对，使用情感支持和自我照顾。旨在促进适应HCT经历的干预措施应包括一些策略，以帮助护理人员处理困扰症状并促进适应性应对。后者包括适应性策略和适应不良性策略（分别为75％和25％）。尽管消极的思想和情绪占主导地位，但还是出现了适应的迹象，其中提到了积极的心理状态，例如乐观和感激之情，以及适应性应对策略，例如积极应对，使用情感支持和自我照顾。旨在促进适应HCT经历的干预措施应包括一些策略，以帮助护理人员处理困扰症状并促进适应性应对。后者包括适应性策略和适应不良的策略（分别为75％和25％）。尽管消极的思想和情绪占主导地位，但还是出现了适应的迹象，其中提到了积极的心理状态，例如乐观和感激之情，以及适应性应对策略，例如积极应对，使用情感支持和自我照顾。旨在促进适应HCT经历的干预措施应包括一些策略，以帮助护理人员处理困扰症状并促进适应性应对。