Patients with advanced or metastatic urothelial cancer face stark choices. Although platinum-based chemotherapy is the primary treatment for eligible patients, most will progress and life expectancy after progression is less than 1 year. Unlike prostate cancer, where patients have time to undergo a myriad of treatments, a patient with advanced urothelial cancer has a short window of opportunity to attempt to arrest their disease.

中文翻译：

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铂难治性尿路上皮癌患者的关键治疗选择。

患有晚期或转移性尿路上皮癌的患者面临严峻的选择。尽管基于铂的化学疗法是符合条件的患者的主要治疗方法，但大多数疗法都会进展，并且进展后的预期寿命不到1年。与前列腺癌不同，在前列腺癌中，患者有时间接受无数的治疗，而患有晚期尿路上皮癌的患者则有很短的机会尝试阻止其疾病。