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Migrastatics: Redirecting R&D in Solid Cancer Towards Metastasis?
Trends in Cancer ( IF 18.4 ) Pub Date : 2019-11-16 , DOI: 10.1016/j.trecan.2019.10.011
Daniel Rosel 1 , Michael Fernandes 2 , Victoria Sanz-Moreno 3 , Jan Brábek 1
Affiliation  

The concept of 'migrastatics' allows the development of a new drug class that is neither cytotoxic nor antiproliferative but is solely directed towards inhibition of cancer cell motility. Given that the regulatory pathway is open, and migrastatic candidates have been described, it is the right time to enter a new era of antimetastatic treatment.



中文翻译:

偏头痛患者:将实体癌的研发转向转移?

“偏头痛药”的概念允许开发既不具有细胞毒性也不具有抗增殖作用,而仅针对抑制癌细胞运动的新药。鉴于监管途径是开放的,并且已经描述了可迁移的候选药物,现在正是进入抗转移治疗新时代的合适时机。

更新日期:2019-11-16
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