Type 2 diabetes mellitus (T2DM) is an endocrine metabolic disorder, occurring worldwide due to aging, advancement in lifestyle by modernization. T2DM is characterized by higher levels of glucose in the blood due to unresponsive secretion of pancreatic insulin and insulin activity or altogether. T2DM is regarded as a powerful genetic susceptible disease that leads to high risk with insulin resistance and β‐cell dysfunction. To manage and overcome type 2 diabetes, physical activity, diet strategies, and other therapeutic medications along with usage of antiglycemic agents are developed and attempted appropriately. In the present review, attention has been focused on the understanding of T2DM outcomes, complications with possible management strategies, and pathophysiology of T2DM. Further, a detailed note on antiglycemic agents in use and other possible drugs of choice was discussed in the light of current preventive strategies are presented in this review.

中文翻译：

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洞察2型糖尿病的现状和进展以及避免并发症：概述

2型糖尿病（T2DM）是一种内分泌代谢疾病，由于衰老，现代化导致的生活方式改善，在全世界范围内发生。T2DM的特征是由于胰腺胰岛素无反应的分泌和胰岛素活性或完全导致血液中葡萄糖水平升高。T2DM被认为是一种强大的遗传易感疾病，会导致胰岛素抵抗和β细胞功能异常的高风险。为了控制和克服2型糖尿病，人们开发并尝试了体育锻炼，饮食策略和其他治疗药物以及抗血糖药的使用。在本综述中，注意力集中在对T2DM结局，可能的治疗策略的并发症以及T2DM的病理生理学的理解上。进一步，