Carcinoma cells often acquire mobility and invasiveness by undergoing epithelial-to-mesenchymal transition, and yet most metastatic lesions remain epithelial in nature. Recently, in Nature, Padmanaban et al. (2019) demonstrated that the quintessential epithelial marker E-cadherin promotes metastasis of invasive ductal breast carcinoma by enhancing the survival of tumor cells.

中文翻译：

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角色逆转：E-钙黏着蛋白的促转移功能。

癌细胞通常通过经历上皮到间充质的转变而获得活动性和侵袭性，但是大多数转移性病变本质上仍然是上皮。最近，在《自然》杂志上，Padmanaban等人。（2019）证明了典型的上皮标记物E-cadherin通过提高肿瘤细胞的存活率来促进浸润性导管癌的转移。