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Imaging: Gear up for mechano-immunology.
Cellular Immunology ( IF 4.3 ) Pub Date : 2019-05-16 , DOI: 10.1016/j.cellimm.2019.103926
Zhengpeng Wan 1 , Samina Shaheen 2 , Alicia Chau 2 , Yingyue Zeng 3 , Wanli Liu 4
Affiliation  

Immune cells including B and T lymphocytes have a remarkable ability to sense the physical perturbations through their surface expressed receptors. At the advent of modern imaging technologies paired with biophysical methods, we have gained the understanding of mechanical forces exerted by immune cells to perform their functions. This review will go over the imaging techniques already being used to study mechanical forces in immune cells. We will also discuss the dire need for new modern technologies for future work.



中文翻译:

影像学:为机械免疫做准备。

包括B和T淋巴细胞在内的免疫细胞具有通过其表面表达的受体感知物理扰动的显着能力。随着现代成像技术与生物物理方法的结合,我们已经了解了免疫细胞为执行其功能而施加的机械力。这篇综述将回顾已经用于研究免疫细胞机械力的成像技术。我们还将讨论对未来工作迫切需要的新现代技术。

更新日期:2019-11-18
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