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Endoscopic submucosal dissection in the rectum with a novel tissue retraction device
Digestive Endoscopy ( IF 5.3 ) Pub Date : 2019-11-17 , DOI: 10.1111/den.13551
Mayenaaz Sidhu 1, 2 , Michael J Bourke 1, 2
Affiliation  

ENDOSCOPIC SUBMUCOSAL DISSECTION (ESD) allows en-bloc, R0 resection of large (>20 mm) laterally spreading colonic lesions (LSL) minimizing recurrence risk and potentially curing low-risk submucosal invasive cancer (SMIC). However, colonic ESD is technically challenging, time-consuming and resource intensive which has limited its adoption in the West. Modifications are needed to improve the ease and efficiency of the procedure especially given its suitability for the subgroup of lesions at high risk of SMIC. The first case is a 74-year-old woman with a 40-mm, Paris 0-IIa + Is, granular, mid-rectal LSL (Video S1). The second case is a 72-year-old man with a 50-mm, Paris 0-IIa + Is, granular distal rectal LSL (Video S2). After careful lesion evaluation, full circumferential mucosal incision is carried out prior to insertion of the retraction device using the 1.5 mm Dual Knife (Olympus, Tokyo, Japan). The submucosal injectate comprised a colloid solution (Gelofusine; B. Braun Australia, Bella Vista, Australia) combined with 0.2% indigo carmine blue and epinephrine diluted to 1: 100,000. The distal margin includes 1 cm of normal mucosa to create a flap of tissue for grasping. The overtube is then inserted, and grasping forceps are introduced through the accessory channel (Fig. 1). The distal flap is then clasped Figure 2 Grasping forceps for tissue manipulation in 360degree plane.

中文翻译:

使用新型组织牵开装置进行直肠内窥镜黏膜下剥离术

内镜黏膜下层剥离术 (ESD) 允许整块、R0 切除大(> 20 毫米)横向扩散的结肠病变 (LSL),最大限度地降低复发风险并有可能治愈低风险黏膜下浸润癌 (SMIC)。然而,结肠 ESD 在技术上具有挑战性、耗时且资源密集,这限制了其在西方的采用。需要进行修改以提高程序的简便性和效率,特别是考虑到它适用于 SMIC 高风险的病变亚组。第一个病例是一名 74 岁女性,患有 40 毫米、Paris 0-IIa + Is、颗粒状、中直肠 LSL(视频 S1)。第二个病例是一名 72 岁男性,患有 50 毫米、Paris 0-IIa + Is、颗粒状远端直肠 LSL(视频 S2)。经过仔细的病变评估,在使用 1.5 mm 双刀(Olympus,Tokyo,Japan)插入牵开装置之前进行全周粘膜切口。粘膜下注射液包含胶体溶液(Gelofusine;B. Braun Australia,Bella Vista,澳大利亚)与稀释至 1:100,000 的 0.2% 靛蓝胭脂红和肾上腺素。远端边缘包括 1 厘米的正常粘膜,以创建用于抓握的组织瓣。然后插入套管,并通过辅助通道引入抓钳(图 1)。然后扣紧远端皮瓣。 图 2 夹钳用于 360 度平面组织操作。2% 靛蓝胭脂红和肾上腺素稀释至 1:100,000。远端边缘包括 1 厘米的正常粘膜,以创建用于抓握的组织瓣。然后插入套管,并通过辅助通道引入抓钳(图 1)。然后扣紧远端皮瓣。 图 2 夹钳用于 360 度平面组织操作。2% 靛蓝胭脂红和肾上腺素稀释至 1:100,000。远端边缘包括 1 厘米的正常粘膜,以创建用于抓握的组织瓣。然后插入套管,并通过辅助通道引入抓钳(图 1)。然后扣紧远端皮瓣。 图 2 夹钳用于 360 度平面组织操作。
更新日期:2019-11-17
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