Peripheral blood mononuclear cells (PBMCs) were collected from a 6-year-old female child who was clinically diagnosed as primary nephrotic syndrome (NS) with hormone resistance. An iPSC line was successfully established by the Sendai-virus (SeV) delivery system. The iPS-19 (GSPHi001-A) expressed pluripotent markers, exhibited a normal karyotype and differentiated towards three germ layers. The iPSC line might offer a potentially useful tool for investigating mechanisms of primary NS, drug testing and gene therapy studies.

中文翻译：

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从一名6岁的患有肾病综合征的女性中诱导多能干细胞系（GSPHi001-A）的建立。

从临床诊断为激素抵抗的原发性肾病综合征（NS）的6岁女童中收集外周血单个核细胞（PBMC）。通过仙台病毒（SeV）传送系统成功建立了iPSC线。iPS-19（GSPHi001-A）表达了多能标记，表现出正常的核型，并向三个胚层分化。iPSC产品线可能为研究原发性NS，药物测试和基因治疗研究的机制提供潜在的有用工具。