The development of antibacterial implant surfaces is a challenging task in biomaterial research. We fabricated a highly antibacterial bimetallic platinum (Pt)/silver(Ag) nanopatch surface by short time sputtering of Pt and Ag on titanium. The sputter process led to a patch-like distribution with crystalline areas in the nanometer-size range (1.3-3.9 nm thickness, 3-60 nm extension). Structural analyses of Pt/Ag samples showed Ag- and Pt-rich areas containing nanoparticle-like Pt deposits of 1-2 nm. The adhesion and proliferation properties of S. aureus on the nanopatch samples were analyzed. Consecutively sputtered Ag/Pt nanopatches (Pt followed by Ag) induced enhanced antimicrobial activity compared to co-sputtered Pt/Ag samples or pure Ag patches of similar Ag amounts. The underlying sacrificial anode mechanism was proved by linear sweep voltammetry. The advantages of this nanopatch coating are the enhanced antimicrobial activity despite a reduced total amount of Ag/Pt and a self-limited effect due the rapid Ag dissolution.

中文翻译：

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通过牺牲阳极机制增强了超薄银/铂纳米贴片的抗菌性能。

在生物材料研究中，抗菌植入物表面的开发是一项艰巨的任务。我们通过在钛上短时间溅射Pt和Ag制备了高度抗菌的双金属铂（Pt）/银（Ag）纳米贴片表面。溅射过程导致了类似补丁的分布，其晶体区域在纳米尺寸范围内（1.3-3.9 nm厚度，3-60 nm延伸）。Pt / Ag样品的结构分析表明，富含Ag和Pt的区域包含1-2 nm的纳米颗粒状Pt沉积物。分析了金黄色葡萄球菌在纳米斑样品上的粘附和增殖特性。与共同溅射的Pt / Ag样品或类似Ag量的纯Ag片相比，连续溅射的Ag / Pt纳米片（Pt继之以Ag）诱导了增强的抗菌活性。通过线性扫描伏安法证明了潜在的牺牲阳极机理。尽管减少了Ag / Pt的总量，但这种纳米补丁涂层的优势是增强了抗菌活性，并且由于Ag的快速溶解而产生了自限效应。