Two new flavones, 8,4′-dimethoxy-6-(2-oxopropyl)-flavone (1) and 8,4′-dimethoxy-6-(3-hydroxypropyl)- flavone (2), were isolated from the seeds of Arctium lappa. Their structures were elucidated by spectroscopic methods, including extensive 1D and 2D NMR techniques. Compounds 1 and 2 were evaluated for their anti-methicillin-resistant Staphylococcus aureus (anti-MRSA) activity. The results showed that compounds 1 and 2 exhibited weak active with diameter of inhibition zone (IZD) 10.8 ± 1.0 and 9.3 ± 0.8 mm, respectively. Compounds 1 and 2 were also tested for antioxidant activity, and they show good antioxidant activity with IC50 values of 3.85 and 3.47 μg/mL, respectively.

中文翻译：

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牛蒡种子的两种新黄酮及其生物活性

从种子中分离出两种新的黄酮，8,4'-二甲氧基-6-(2-氧代丙基)-黄酮 (1) 和 8,4'-二甲氧基-6-(3-羟丙基)-黄酮 (2)牛蒡。它们的结构是通过光谱方法阐明的，包括广泛的 1D 和 2D NMR 技术。评估了化合物 1 和 2 的抗甲氧西林金黄色葡萄球菌（抗 MRSA）活性。结果表明，化合物1和2表现出弱活性，抑菌圈直径(IZD)分别为10.8±1.0和9.3±0.8mm。还测试了化合物 1 和 2 的抗氧化活性，它们显示出良好的抗氧化活性，IC50 值分别为 3.85 和 3.47 μg/mL。