This study was performed to evaluate the effects of omega-3 supplementation on growth performance, clinical signs, post-mortem lesions, haemagglutination inhibition (HI) antibody titres, gene expression and histopathology in quails (Coturnix coturnix japonica) infected with Newcastle disease virus (NDV) and avian influenza virus (AIV) H9N2. One hundred, 40-day-old male quails were divided into 5 groups: G1, fed a control basal diet; G2A, infected with NDV; G2B, infected with H9N2; G3A, infected with NDV and given omega-3, and G3B, infected with H9N2 and given omega-3. The dietary omega-3 supplementation was continued for 4 weeks: two weeks before infection and two weeks after intranasal infection with virulent NDV and AIV H9N2. Our results revealed significant differences (P < 0.05) in growth performance, HI antibody titres, clinical signs, post-mortem lesions, mortality, viral shedding rates, immunological parameters, and histopathological lesions between the treated (G3A and G3B) and untreated (G2A and G2B) groups. In conclusion, dietary omega-3 supplementation for 4 weeks can improve growth performance and alleviate the deleterious immunological and pathological effects of NDV and AIV H9N2 infection in quails.

中文翻译：

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富含omega-3的饮食对感染新城疫病毒或禽流感病毒H9N2的日本鹌鹑（Coturnix coturnix japonica）反应的影响。

这项研究旨在评估补充omega-3对新城疫病毒感染的鹌鹑（Coturnix coturnix japonica）的生长性能，临床体征，死后病变，血凝抑制（HI）抗体滴度，基因表达和组织病理学的影响。 NDV）和禽流感病毒（AIV）H9N2。一百只40天大的雄性鹌鹑分为5组：G1，喂食基础基础饮食； G1，喂食基础基础饮食； G1，喂食基础基础饮食。G2A，感染了NDV；G2B，感染了H9N2；G3A受NDV感染并给予omega-3，G3B受H9N2感染并给予omega-3。饮食中的omega-3补充持续4周：感染前两周和鼻内感染强毒NDV和AIV H9N2后两周。我们的结果显示，在生长性能，HI抗体滴度，临床体征，治疗组（G3A和G3B）与未治疗组（G2A和G2B）之间的死后病变，死亡率，病毒脱落率，免疫学参数和组织病理学病变。总之，在饮食中补充4周的omega-3可以改善生长性能并减轻鹌鹑NDV和AIV H9N2感染的有害免疫学和病理学影响。