Synovial membrane inflammation is common in osteoarthritis (OA) and increases cartilage injury. However, synovial fluid and histology studies suggest that OA inflammatory responses are not homogeneous. Greater understanding of these responses may provide new insights into OA disease mechanisms. We undertook this study to develop a novel multiparameter approach to phenotype synovial responses in knee OA.

中文翻译：

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多参数分析确定了膝骨关节炎滑膜反应的异质性。

滑膜发炎在骨关节炎（OA）中很常见，会增加软骨损伤。但是，滑液和组织学研究表明OA炎症反应不是均一的。对这些反应的更多了解可能为OA疾病机制提供新的见解。我们进行了这项研究，以开发一种新颖的多参数方法来处理膝骨关节炎的表型滑膜反应。