The strong spatial confinement of a nanocavity plasmonic field has made it possible to visualize the inner structure of a single molecule and even to distinguish its vibrational modes in real space. With such ever-improved spatial resolution, it is anticipated that full vibrational imaging of a molecule could be achieved to reveal molecular structural details. Here we demonstrate full Raman images of individual vibrational modes at the ångström level for a single Mg-porphine molecule, revealing distinct characteristics of each vibrational mode in real space. Furthermore, by exploiting the underlying interference effect and Raman fingerprint database, we propose a new methodology for structural determination, which we have called ‘scanning Raman picoscopy’, to show how such ultrahigh-resolution spectromicroscopic vibrational images can be used to visually assemble the chemical structure of a single molecule through a simple Lego-like building process.

中文翻译：

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通过扫描拉曼显微镜可视化构建单个分子的化学结构

纳米腔等离子体场的强空间限制使可视化单个分子的内部结构成为可能，甚至可以区分真实空间中的振动模式。随着空间分辨率的不断提高，预计可以实现分子的全振动成像以揭示分子结构细节。在这里，我们展示了单个 Mg-卟吩分子在 ångström 级别的各个振动模式的完整拉曼图像，揭示了真实空间中每种振动模式的不同特征。此外，通过利用潜在的干扰效应和拉曼指纹数据库，我们提出了一种新的结构确定方法，我们称之为“扫描拉曼显像”，