The specific cellular role of mitochondria is influenced by the surrounding environment because effective mitochondrial function requires the delivery of inputs (e.g., oxygen) and export of products (e.g., signaling molecules) to and from other cellular components, respectively. Recent technological developments in mitochondrial imaging have led to a more precise and comprehensive understanding of the spatial relationships governing the function of this complex organelle, opening a new era of mitochondrial research. Here, I highlight current imaging approaches for visualizing mitochondrial form and function within complex cellular environments. Increasing clarity of mitochondrial behavior within cells will continue to lend mechanistic insights into the role of mitochondria under normal and pathological conditions and point to spatially regulated processes that can be targeted to improve cellular function.

中文翻译：

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可视化细胞内的线粒体形式和功能。

线粒体的特定细胞作用受周围环境的影响，因为有效的线粒体功能需要分别向其他细胞成分和从其他细胞成分传递输入（例如氧气）和产品（例如信号分子）输出。线粒体成像的最新技术发展已导致对控制这种复杂细胞器功能的空间关系的更精确和全面的了解，从而开启了线粒体研究的新纪元。在这里，我重点介绍了用于在复杂细胞环境中可视化线粒体形式和功能的当前成像方法。