Accumulation-mediated chemical reactions are a ubiquitous phenomenon in nature. Here, we explore microbubble-induced accumulation of precursor ions to achieve surfactant-free synthesis of immiscible metallic nanoalloys and simultaneously pattern the nanoalloys into targeted architectures for their enhanced catalytic applications. Our unified spatiotemporal synthesis and structuring (US³) strategy, whereby millisecond-scale accumulation of the ions takes place in a highly confined laser-mediated microbubble trap (MBT), drives ultrafast alloy synthesis in sync with the structuring process. As a case in point, we employ the US³ strategy for the in situ surfactant-free synthesis and patterning of traditionally immiscible rhodium-gold (RhAu) nanoalloys. Stochastic random walk simulations justify the millisecond-scale accumulation process, leading to a 3-order reduction in synthesis time. The catalytic activity and structure-property relationship were evaluated using the reduction of p-nitrophenol with NaBH₄. Our in situ synthesis and structuring strategy can be translated for high-throughput production and screening of multimetallic systems with tailored catalytic, optoelectronic, and magnetic functions.

积累介导的化学反应是自然界普遍存在的现象。在这里，我们探讨了微气泡诱导的前体离子累积，以实现无表面活性剂的不混溶金属纳米合金的合成，并同时将纳米合金图案化为目标结构，以增强其催化应用。我们统一的时空合成和结构化（US ³）策略，即离子的毫秒级累积在高度受限的激光介导的微气泡阱（MBT）中发生，与结构化过程同步地推动了超快合金的合成。举例来说，我们在原地采用了US ³策略传统上不混溶的铑金（RhAu）纳米合金的无表面活性剂合成和构图。随机随机游走模拟证明了毫秒级累加过程的合理性，从而使合成时间减少了3阶。通过用NaBH ₄还原对硝基苯酚来评估催化活性和结构性质关系。我们的原位合成和结构化策略可以转化为具有特定催化，光电和磁功能的多金属系统的高通量生产和筛选。