New evidence indicates the importance of CD137 for controlling Epstein-Barr virus (EBV) infections. (1) Mutations in CD137 predispose to EBV-associated diseases. (2) EBV induces ectopic CD137 expression, thereby activating a negative feed-back regulation and reducing T cell costimulation. These findings suggest CD137 agonists as new treatments for EBV-associated diseases.

中文翻译：

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毁了，什么毁了你。

新证据表明CD137在控制爱泼斯坦巴尔病毒（EBV）感染中的重要性。（1）CD137突变易患EBV相关疾病。（2）EBV诱导异位CD137表达，从而激活负反馈调节并减少T细胞共刺激。这些发现表明CD137激动剂是与EBV相关疾病的新疗法。